Ultrasound-guided FNAC showed the highest level of agreement with histology for exact N classification. Ultrasound-guided FNAC showed the smallest percentage of overstaged patients, 7%, versus 16% with PET/CT, 13% with CT, and 13% with ultrasound. The rate of understaged patients was comparable between the imaging modalities. With regard to the endpoint N0 versus N+ there were no statistically significant differences to be found.

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Home >> Clinical Otolaryngology, Volume 36, Number 2

Preoperative circulating C-reactive protein levels predict pathological aggressiveness in oral squamous cell carcinoma: A retrospective clinical study

Authors: Chen, H.-H.; Chen, I.-H.; Liao, C.-T.¹; Wei, F.-C.²; Lee, L.-Y.³; Huang, S.-F.¹

Source: Clinical Otolaryngology, Volume 36, Number 2, April 2011 , pp. 147-153(7)

Publisher: Wiley-Blackwell

 

Jó lehet, egyszerűen mérhető

Ez nem is hangzik rosszul, kérdéses, hogy van-e értelme

Szerintem felesleges

Jó ötlet, de kevés az elemszám, és nincs normál kontroll csoport

Balloon dilation of the cartilaginous portion of the eustachian tube: initial safety and feasibility analysis in a cadaver model☆☆☆

 

 

 

Received 25 October 2009 published online 14 April 2010.

Abstract 

Background

Balloon catheter dilation of diseased sinus ostia has recently demonstrated efficacy and safety in the treatment of chronic sinus disease with 2 years of follow-up. Similar to sinus surgery, initial studies of partial resection of inflamed mucosa from within the cartilaginous eustachian tube (ET) have demonstrated efficacy and safety in the treatment of medically refractory otitis media with effusion. Therefore, balloon dilation of the cartilaginous ET was investigated as a possible treatment modality for otitis media.

Methods

A protocol for sinus balloon catheter dilation was evaluated in each of the cartilaginous ETs in 8 fresh human cadaver heads. Computed tomographic scans and detailed endoscopic inspections with video or photographic documentation were performed pre- and posttreatment, and gross anatomical dissections were done to analyze the effects of treatment and to look for evidence of undesired injury.

Results

Catheters successfully dilated all cartilaginous ETs without any significant injuries. There were no bony or cartilaginous fractures, and 3 specimens showed minor mucosal tears in the anterolateral or inferior walls. Volumetric measurements of the cartilaginous ET lumens showed a change from an average of 0.16 to 0.49 cm3 (SD, 0.12), representing an average increase of 357% (range, 20–965%).

Conclusions

Balloon catheter dilation of the nasopharyngeal orifice of the ET was shown to be feasible and without evidence of untoward injury. A significant increase in volume of the cartilaginous ET was achieved. A clinical study is now indicated to determine whether balloon dilation will demonstrate lasting benefits and safety in the treatment of otitis media.

Mindig Z. Szabó prof. előadása jár az eszemben ilyenkor, és olyankor elmegy a kedvem a tuba piszkálásától.